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Secondary flavoproteome defects can be further subcategorized into primary mitochondrial disorders (PMD) and secondary mitochondrial dysfunction (SMD) [17]

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The conditions under which PknG is stimulated to phosphorylate or dephosphorylate GarA has not yet been investigated and it is not clear how the relationship between GarA, NAD + -GDH and PknG may impact nitrogen metabolism in the mycobacteria