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Xing Y, Wang X, Guo X, Yang P, Yu J, Shui Y, et al

The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology

PMID 22666519

E.AskinF.HamvasA.WhitsettJ

An extra lysine residue is added beyond the endogenous sequence, bearing a chemical modification referred to as N-3-maleimidopropionic acid (MPA)

Community data suggests 10-15% of users notice mild sleep disruption, almost always tied to evening injection timing