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While normal wound healing progresses through controlled inflammation, proliferation, and remodeling, chronic wounds disrupted by bacterial biofilms experience prolonged inflammation, impaired angiogenesis, and delayed tissue restoration

Drug delivery systems comprising bioadhesive polymers are known to reduce the rate of clearance of drug molecules from the absorption site, thus prolonging the time available for absorption

In some cases, it can reduce healing time by 30-50%

The peptide has been studied extensively in animal models since the 1990s, with over 100 published research papers examining its effects on various tissues and conditions

Subcutaneous formalin and intraplantar carrageenan increase nitric oxide release as measured by in vivo voltammetry in the spinal cord