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Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H

In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with semaglutide 0.5 and 1 mg once weekly injections (3%) compared to placebo (1.8%)
Materials and Methods The study was a randomized, double-blind, placebo-controlled trial (registered at clinicaltrials.gov as NCT00641862)

However, older adults may have a more challenging time absorbing B12 from their diet, so it may be necessary to supplement this vitamin

This makes regular injections on a maintenance schedule the most effective way to sustain optimal energy, neurological function, and metabolic support over time
