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That means you should interpret results cautiously effect sizes in rodent cognition studies often don't translate 1:1 to humans

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In contrast, in mTYR, the Val377 and Ser380 are replaced with proline (P257) and alanine (A260), respectively, therefore it can be considered that there is little VdW clashes of the isopropyl group of -thujaplicin with A260 and P257 (Figure 16)

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