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Eur J Clin Invest 50(4):e13211

Green tea catechins like epigallocatechin-3-gallate (EGCG) and grape seed proanthocyanidins (GSPs) exhibit photoprotective properties by absorbing UVA and UVB radiation, reducing DNA damage, and inhibiting UVB-induced cyclooxygenase-2 (COX-2) expression, which is critical in the development of skin tumors 139

A typical cycle lasts approximately 45 days

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Overall, numerous results suggest that extracellular HMGB1 is involved in the pathogenesis of SLE

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