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When prostate cancer cells were compared in environments with varying levels of folic acid, those exposed to lower concentrations exhibited notable genetic and epigenetic instability along with observable phenotypic changes

found that in pancreatic cancer patients, the expression of ubiquitin-specific protease 8 (USP8) is increased, and USP8 stabilizes NRF2 expression by deubiquitinating K48-linked polyubiquitin chains on NRF2

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Minor metabolizer = m Modified from Samer et al

Crume TL, Ogden L, Maligie M, Sheffield S, Bischoff KJ, McDuffie R et al (2011) Long-term impact of neonatal breastfeeding on childhood adiposity and fat distribution among children exposed to diabetes in utero

doi: 10.1517/17425247.2015.984683