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The SELECT trial, enrolling over 17,000 patients with established cardiovascular disease over nearly 40 months, confirmed the cardiovascular safety of semaglutide and demonstrated net benefit in a high-risk population

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Studies have examined retatrutide in preclinical and clinical settings involving GLP-1, GIP, and glucagon receptor signaling and downstream metabolic endpoints

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We prefer subcutaneous, because it is painless, effective, very easy to do by yourself, and carries no risk of nerve injury