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Elevated levels of 2-hydroxyglutarate, a metabolite associated with the TCA cycle, may promote tumorigenesis [51]

[DOI] [PubMed] [Google Scholar] 75.Chen Y., Vartiainen N.E., Ying W., Chan P.H., Koistinaho J., Swanson R.A

In a study of 57 patients with stiff-person syndrome followed for greater than 5 years, 80% exhibited some degree of disability progression (63)

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10.1016/0304-4165(85)90182-5 Biochim

Results Demographics and Attributions One hundred forty-one patients of 155 who were treated a year or more ago and who responded to our follow-up formed the basis for this report