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Table 1 Key preclinical and clinical findings of targeting ferroptosis, pyroptosis, and necroptosis in melanoma

Vitamin B12 Deficiency Treatment: For anemia, nerve pain, memory loss, and absorption disorders (common in older adults and vegans)

Nitric Oxide System Interaction: The peptide interacts with the nitric oxide system, which regulates blood vessel dilation and blood flow

The effect of 20 M chromium (VI) on annexin V binding was partially reversed when Ca 2+ was removed

Furthermore, injectable peptides offer advantages in settings requiring precise dosing control and documentation of administration