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Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes

The bile acid TUDCA reduces age-related hyperinsulinemia in mice

[DOI] [PMC free article] [PubMed] [Google Scholar] 294.Wang XZ

10.1002/2211-5463.12816 FEBS Open Bio

3) as measured by the decrease in absorbance of NADPH at 340 nm

Moreover, our study strongly implicates elevated 4-HNE generation as a key contributor to the ROS mediated deterioration of the ageing oocyte via the adduction of key meiotic proteins including members of the tubulin family
