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This regimen yielded significant bacterial clearance and stimulated granulation tissue formation, attesting to ozone therapy potential as a reliable intervention [16]

In spite of the relevant issues mentioned above, the development of the first commercially available drug delivery system and advances in knowledge about in vivo results are important steps forward toward optimized design of more efficient formulations
Ryan S, Kokotailo P, Camenga D , Patrick S, Plumb J, Quigley J, Walker-Harding L

105 Thus, the choice of carrier should be tailored to the physicochemical properties of the therapeutic agent and the desired pharmacological outcome

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