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Description
Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia

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Nuclear gene regulation: Overexpression of PGC-1 (peroxisome proliferator-activated receptor gamma coactivator 1-alpha) can activate the NRF1/TFAM pathway, driving the expression of genes related to mitochondrial biogenesis (such as COX5B, ATP5F1), and enhancing mitochondrial DNA (mtDNA) replication and respiratory chain complex assembly (99101)

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