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Sciatic nerve regeneration in mice and rats: recovery of sensory innervation is followed by a slowly retreating neuropathic pain-like syndrome

DOX exerts direct toxic damage to the glomerular base membrane, podocytes, and glomerular endothelial cells, inducing tubular interstitial inflammation and fibrosis[32]

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Important Safety Information Contraindications and Precautions: Joint injections should only be performed by qualified medical professionals Active joint infection is an absolute contraindication to intra-articular injection Bleeding disorders or anticoagulation therapy may increase injection risks Pregnancy and breastfeeding: no safety data available, avoid use Cancer history: while AOD-9604 does not affect IGF-1, consult oncologist before use Monitoring Recommendations: Regular follow-up with joint imaging and functional assessments to evaluate treatment response

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