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Funding: This work was supported by the University of WittenHerdecke, Germany

10.1073/pnas.0806192105 116 HardyJ

Comparative analysis with other emerging modalities, including monoclonal antibodies, GLP-1 analogs, gene editing tools, and microbiome modulators, suggests that integrated strategies combining nanotechnology with molecular inhibition may offer the most effective path forward

These needles have a smaller gauge and shorter length

Short peptides, which exhibit high accessibility and diverse effects, hold promise

For optimal results, rotate the patch between the placements that provide you the most control of your appetite