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Although the analysis of findings suggested favorable effects for nerve growth factor, the researchers were unable to draw a firm conclusion due to low quality and quantity of evidence

Yermolaieva et al., 2004), among which ASIC1a and ASIC3 are expressed in both MSCs and NP-MSCs (Li et al., 2014a

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What I want you to take from this is that there's a whole category of treatments between "live with it" and surgery, and they work
