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To test this hypothesis we designed a randomized double-blind placebo-controlled trial involving 200 older people aged 75 years or greater who were randomly allocated to receive either a daily oral tablet containing 1 mg vitamin B12 or a matching placebo tablet

High doses can be helpful in treating vitamin B12 deficiency, but megadosing without reason may not offer extra benefits and could mask other nutrient imbalances

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[PubMed] [Google Scholar] 45.Krause BR, Phares F, Serbin V, Krause L, Hartman AD

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