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Hence, lung injury is a more serious disorder compared with pneumonia

However, an impairment in the respiratory burst was observed in granulocytemacrophage colony-stimulating factor (GM-CSF)-matured MDMs and alveolar macrophage-like (AML) cells 2 from both patients with TNF deficiency, TNF- or TNFR1-deficient induced pluripotent stem (iPS)-cell-derived GM-CSF-matured macrophages, and healthy control MDMs and AML cells differentiated with TNF blockers in vitro, and in lung macrophages treated with TNF blockers ex vivo

Maltarollo, V

Clin Transl Med 15:e70271

Houston M, Harper K

The renin-angiotensin-aldosterone system (RAAS) plays a key role in normal water and sodium homeostasis and RAAS activation is an important contributor in human primary hypertension (416)
