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Ohashi et al., 2002

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It is a quaternary ammonium compound that the body synthesizes from the amino acids lysine and methionine, primarily in the liver, kidneys, and brain

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(2012) 7:e37210

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TMA can be oxidized to TMAO through the liver and intestines (jejunum and cecum) and enter the blood circulation

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Humans express four angiopoietin family member proteins (ANGPT1ANGPT4) that exert their effects by binding to two related receptors called tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE1

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Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons

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