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Description
Ohashi et al., 2002

It is a quaternary ammonium compound that the body synthesizes from the amino acids lysine and methionine, primarily in the liver, kidneys, and brain
(2012) 7:e37210
TMA can be oxidized to TMAO through the liver and intestines (jejunum and cecum) and enter the blood circulation

Humans express four angiopoietin family member proteins (ANGPT1ANGPT4) that exert their effects by binding to two related receptors called tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE1
Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons
