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The peptide exhibits consistent efficacy in models of acute and chronic injury regardless of administration route (intraperitoneal, oral, or local application), a unique characteristic distinguishing it from other growth factors that typically require localized delivery with carrier systems
Singh SP, Wishnok M, Keshive M, Deen WM, Tannenbaum SR
doi: 10.1158/1078-0432.ccr-17-0696
P2Y2R deficiency ameliorates hepatic steatosis by reducing lipogenesis and enhancing fatty acid -oxidation through AMPK and PGC-1 induction in high-fat diet-fed mice
Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Windhauser MM, Lin PH, Karanja N
