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The design integrates several key components, as outlined below: the chosen CBBBP is Tat, identified through prior animal experimentation from two candidate peptides for its superior efficacy in facilitating the transport of therapeutic agents crossing BBB

Additionally, mitochondrial-derived peptide-c (MOTS-c) has been shown to reverse mitochondrial dysfunction and reduce oxidative stress, thereby alleviating metabolic reprogramming, decreasing beta-oxidation, and increasing glycolytic flux influenced by abnormal metabolism during myocardial infarction [464]

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He has received single-center research grants from Takeda to study TAK-954 and from Vanda to study tradipitant

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