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10.1158/1078-0432.CCR-22-2791 73

SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC

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These data demonstrate that GGCT enzymatically diverts Gln flux away from the TCA cycle, preferentially shunting Gln toward GSH synthesis to sustain redox homeostasis

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