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Coenzyme Q(10) in submicron-sized dispersion improves development, hatching, cell proliferation, and adenosine triphosphate content of in vitro -produced bovine embryos

This study was supported by the National Natural Science Foundation of China (82030037, 81801288, and 81871009), STI2030-Major Projects (2021ZD0201801), and the Translational and Application Project of Brain-Inspired and Network Neuroscience on Brain Disorders, Beijing Municipal Health Commission (11000022T000000444685)

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Additionally, caloric restriction can counteract age-dependent increases in specific miRNAs associated with apoptosis, including miR-181a-1*, miR-30e, and miR-34a, to promote cellular survival [88]

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This evidence dates back to seminal work from Harry Eagle, where supplementation with extracellular GSH was suggested to support cell growth in cystine-free conditions 37