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The fact that wild-type ATXN3 binds to components of the transcriptional machinery in cells, as well as the transcriptional changes reported in animal models of SCA3 in the presymptomatic phase, favors the theory of a general transcriptional dysregulation as an initiating factor of SCA3 [117,118,119]

Yehuda & Mostofsky, 1989), but the modification has not yielded a binding probe that resolves the receptor question

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Storage guide for refrigerated peptide solutions, BAC water, room temperature exposure, and degradation signs

47 assayed PR3-ANCA in 283 UC and 208 CD patients with a chemiluminescent immunoassay, and detected it in 31.1% of UC vs