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Lysosome dysfunction as a cause of neurodegenerative diseases: lessons from frontotemporal dementia and amyotrophic lateral sclerosis

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Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (41)

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Association between genetic polymorphisms of glutathione Stransferase M1/T1 and psoriasis in a population from the area of the strict of messina (southern Italy)