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Additionally, animal studies have demonstrated that L-carnitine supplementation encourages protein anabolism by activating the IGF-1/PI3K/Akt signaling pathway and downregulating genes of the ubiquitinproteasome system in skeletal muscle [36, 37]

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however, the results available so far require independent corroboration

doi: 10.1017/S1368980012004314

Nat Rev Neurosci 19: 6380, 2018