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Unlike injectable GLP-1 receptor agonists, bacterial systems exhibit high inter-individual variability in peptide expression and secretion, influenced by diet, baseline microbiota composition, and immune status
Contribution of small G proteins, SNARE proteins and signaling pathways to BDNF secretion Different proteins are involved in the organization of the release site, the transition of BDNF-containing vesicles from the reserve pool to a readily releasable pool, fusion pore opening, as well as disassembly of the SNARE complex
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