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Description
Papalia, F., Jouhra, F., Amin-Youssef, G., Shah, A
XuanJFengWWangJWangRZhangBBoLet al
The latter cluster contained exclusively 5A-1MQ-treated animals switched from WD to LD (the WD/LD-T group), representing ~ 60% of all WD/LD-T animals
It's a medical-grade treatment, which means it uses a stronger blend of acids to penetrate deeper than most at-home products
Our finding that LDHB silencing activates STAT1, a key effector of the INF-/JAK pathway, which suppresses the expression of SLC7A11 is plausibly consistent with the notion that LDH has additional roles beyond glycolysis [23], although the possibility that lactate rather than LDHB itself modulates INF-/JAK pathway activity cannot be completely excluded [67]
2015 Jan 21;48(2):332-9
