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PMID: 24913118 Bridwell, K.H., Anderson, P.A., Boden, S.D., Kim, H.J., Vaccaro A.R., Wang, J.C.: Specialty Update

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The activation of astrocytes exerts highly context-dependent functions that vary along the temporal course of disease, the nature of the pathological milieu and their heterogeneous transcriptional states

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Due to the action of glutathione-S reductase (GSR), which uses electrons from NADPH/H+ to convert GSSG back to the reduced form GSH, the reduced form, which is predominant under normal conditions (Wu J