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Results Inhibition of -oxidation alleviates ER stress in metabolically active cell types We have previously shown in vivo and in hepatoma cells in vitro that inhibiting -oxidation either pharmacologically or genetically diminishes ER stress signaling (Tyra, Spitz, & Rutkowski, 2012)

Anti-inflammatory activity of various superoxide dismutases on polyarthritis in the Lewis rat

Reviews Evidence-Based Approach to Treatment and Prevention of Bronchiectasis

[DOI] [PubMed] [Google Scholar] Rikans LE, Hornbrook KR

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Future studies of oral GSH administration should consider reduced GSH status as an inclusion criteria, demonstrate increased levels of oxidative stress in study candidates prior to inclusion, and/or be performed in populations with increased oxidative burden (e.g., type 2 diabetes)