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developed a pH/redox dual-responsive polyplex for delivering MDR1 siRNA and doxorubicin, which releases its payload in acidic and high GSH environments, demonstrating potent antitumor efficacy [192]

For more info References Holliman BJ, Chyka PA

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By analyzing the pharynx of filipin-stained animals, we found that ncr-2(0) mutants exhibited increased cholesterol levels in the pharynx compared with N2 animals, whereas ncr-1(0) and ncr-1(0)

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