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In short, the change of iron homeostasis and ferroptosis induced by CS plays an important role in COPD occurrence
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This is most likely through the inhibition of antioxidant enzymes such as glutathione peroxidase, which normally functions to detoxify H 2 O 2 and lipid peroxidases [152], and glutathione reductase, preventing the regeneration of GSH from GSSG [153]

[DOI] [PubMed] [Google Scholar] 331.Granata R., Settanni F., Trovato L., Destefanis S., Gallo D., Martinetti M

Cells, 8 (3), 232.

& Bornkamm, G
