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Elevated levels of Thymus-and-Activation-Regulated Chemokine (TARC) and an increased percentage of cells expressing Chemokine Receptor type 4 (CCR4) were observed in patients with more extensive organ involvement and advanced stages of sarcoidosis, relative to those with milder disease manifestations

10.1016/j.brainres.2005.05.057 32

Tang D, Wu D, Hirao A, Lahti JM, Liu L, Mazza B, Kidd VJ, Mak TW and Ingram AJ

Dosage: Initial doses may start at 300 mg daily, divided into multiple doses, with adjustments made based on clinical response

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The highest levels of purine catabolic enzymes in mice are present in the proximal small intestine