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Authors observed that AMDs retinal pigment epithelium (RPE) contains less dense cytoplasm, more lipid droplets, increased glycogen granules, and enlarged autophagosomes [129]

Tissue damage caused by oxidative stress plays a major role in the pathogenesis of social isolation stress 19,20

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Cellular glutathione plays a major role in the defence against redox cycling-derived oxidative stress, either by direct interaction with ROS, RNS and electrophiles, or by acting as a co-factor for various enzymes 11,12