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Oral delivery of a highly stable superoxide dismutase as a skin aging inhibitor

Karnell JL, Kumar V, Wang J, Wang S, Voynova E, Ettinger R

It is generally believed a poor NPB occurs due to reduced muscle protein synthetic responses to exercise, dietary amino acid availability, or an insensitivity of insulin to suppress breakdown

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To test the effect of the putative Munc18-1 Q301 gain or loss of function mutants, syntaxin-1 GUVs were preincubated in the absence or presence of Munc18-1 and subsequently VAMP2/Syt1 SUVs together with soluble SNAP-25 were added (Fig