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They are not considered supplements or medicines and should not be marketed for human consumption

8 BikleD.MajumdarS.LaibA.Powell-BraxtonL.RosenC.BeamerW.et al (2001)
The reduced form of nickel binds very poorly to his-tagged proteins, so if you see this color change, youll likely want to stop your purification
References Smith RG, et al

requires liver toxicity warnings" (Press release)

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