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Yes, MIC B12 injections generally require refrigeration between 36F and 46F (2C to 8C) to maintain chemical stability and potency

FDA in 2014

Mioduchoski, FNP-BC

This study highlights the significant prevalence of Vitamin B12 deficiency and improvement in tinnitus severity scores Vitamin B12 weekly for six weeks further provides a link between cobalamin deficiency and tinnitus thereby suggestive of a therapeutic role of B12 in cobalamin-deficient patients of tinnitus. DON'T MISS Coronavirus new strain: Seven symptoms to watch out for this Christmas [INSIGHT] Covid new strain: Six less obvious signs of Covid-19 to watch out for this Christmas [ADVICE] Bowel cancer warning: Check your toilet paper after wiping - key symptom [TIPS] According to medical website LiveStrong, B-12 is needed to produce myelin, the protective and insulative sheath surrounding nerves

This is done to ensure that you dont have a reaction to the injection