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5 Main Research Findings for MK-677 (Ibutamoren): 5 Main Research Findings for MK-677 (Ibutamoren): Enhances growth hormone (GH) secretion and increases fat-free mass in healthy adults [1], [2] Protects against somatopause (age-associated decline in growth hormone production by the body) [3] Inhibits neuroinflammation and neurodegeneration [4], [5] Improves bone mineral density [1], [6] Increases IGF-1 growth factor levels in adults [7] Selected Clinical Data Selected Clinical Data Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized Trial [1] Growth hormone secretion and muscle mass decline from mid-puberty throughout life, culminating in loss of muscle strength, decreased function, and eventual loss of independence

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DOI References 1

Purinergic Signaling and Redox Homeostasis of the Cell Purinergic signaling affects the activity of antioxidant enzyme systems, contributing to a change in the redox potential of cells (Piacenza et al., 2019