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Mechanism of Action First, afamelanotide acts primarily as an agonist of MC1R , a G-protein-coupled receptor found on melanocytes

The extracted lipid and triglyceride standard (Merck) were then added to a silica gel HL uniplates (Analtech) and developed by a mixture of organic solvents (hexane: dimethyl ether: acetic acid 80:20:3, v/v)

FDA-Approved Compound: Features the active ingredient in FDA-approved Vyleesi

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J Neurosci Res 79:509521 [DOI] [PubMed] [Google Scholar] 19.Carruthers BM, Jain AK, De Meirleir KL, Peterson DL, Klimas NG, Lerner AM, Bested AC, Flor-Henry P, Joshi P, Powles ACP, Sherkey JA, van de Sande MI (2011) Myalgic encephalomyelitis/chronic fatigue syndrome