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Donnelly E, de Water JV, Luckhart S

Visschers et al., 2012

If you are currently taking testosterone replacement therapy, adding HCG can help counteract some of the side effects and reduce the hit you take to your fertility

Notably, the researchers did not observe any change in melatonin levels in young monkeys who were given the same treatment [7]
Retatrutide is still investigational and not approved by any regulator as of April 2026, so everything below is presented as clinical-trial data, not as medical guidance

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Wortley KE, Anderson KD, Garcia K, et al