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Clinical studies also showed that the selective 5-HT 3 antagonist, ondansetron, reduced the incidence and severity of antipsychotic-induced EPS in the schizophrenia treatment (Zhang et al., 2006

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Immunity 39 , 482495 (2013)

Nucleotide specificity was assessed using the G3PDH-coupled assay, as described below, by substituting 5 mM GTP, CTP, or phosphoenolpyruvate (PEP) for ATP at 75 C

These findings remain preliminary and are primarily limited to in vitro and preclinical studies