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Long-term low B12 can drive elevated homocysteine and contribute to megaloblastic or pernicious anemia

Phenylalanine and Tyrosine Catabolism Phenylalanine normally has only two fates: incorporation into polypeptide chains, and hydroxylation to tyrosine via the tetrahydrobiopterin-requiring phenylalanine hydroxylase (PAH) reaction

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PMID: 174 BrownCTDavis-RichardsonAGGiongoAGanoKACrabbDBMukherjeeNet al

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