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Patients receiving B12 injections should inform their healthcare provider of all medications, as certain drugs (including metformin, proton pump inhibitors, and chloramphenicol) can affect B12 absorption or metabolism

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Moreover, previous studies that tried to separate the bacterial contribution to effects on lifespan used a bacterial mutant in the major bacterial glucose transporter 20

Many different organic acid and fatty acid oxidation disorders can be diagnosed using acylcarnitine profiles in blood or plasma samples

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While our findings of neurochemical abnormalities in the pgACC and dACC, in ME/CFS and long COVID patients are intriguing, they must be viewed with caution given the limitations of the study