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JP patent 54,107,594 Tezuka H, Otake Y, Yabuchi S, Kimura H (1987) A novel Saccharomyces promoter and its use in glutathione biosynthesis
doi: 10.1016/S0140-6736(96)07642-8
10.1208/s12249-020-01757-2 15 HuY
This study supports the use of -viniferin (as part of an extract) as a topical treatment for improving facial hyperpigmentation, linking clinical observation with a plausible molecular mechanism
The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin
doi: 10.1093/femsre/fux020 31 DeshpandeRZouC
