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168 A clinical trial in which 128 subjects received 400 mg valerian extract, a commercial valerian product (not otherwise described), and placebo in random order and on three non-consecutive nights found the valerian extract increased subjective sleep quality and shortened the time to fall asleep

van L., David, C.-S., 2007

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It results from atherosclerosis in the peripheral arteries of the legs, which causes an insufficient arterial blood supply during exercise, resulting in anaerobic metabolism in the muscles with the production of lactic acid and other metabolites