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Semin Cell Dev Biol
-GCS is a heterodimeric enzyme composed of a catalytic subunit that is encoded by the GCLC gene and a modifier subunit that is encoded by the GCLM gene [15]

DongZTaiWYangYZhangTLiYChaiYet al
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Likewise, vascular immunotargeting of catalase to lung endothelial cells via anti-angiotensin-converting enzyme antibodies attenuated oxidative damage in a rat model of lung I/R injury (127) ( Table 1 )
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In general, MASLD increases hepatic IR and stimulates the production of proinflammatory cytokines, leading to the development of various CVDs, including atherosclerotic disease and heart failure
