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The oesophageal mucosa responds to acid injury by increasing bicarbonate secretion via carbonic anhydrase-III activity, in an attempt to neutralise the acid (Reference Nortunen, Vkiparta and Parkkila29)

10.1016/j.jpba.2010.07.038 J Pharm Biomed Anal
doi: 10.1016/j.toxicon.2020.03.004

Burgermeister E, Hde P, Betge J et al (2017) Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer

Lakritz J

Tianjin Medical University
