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For example, studies have shown that radioprotection is seen with Vitamin E [36] [37] , lipoic acid, 3,3'-diindolylmethane (DIM) [38] , N-acetylcysteine [39] , glutathione (GSH) [40] , melatonin [37] [41] as well as other compounds [4] [35]

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HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) in the mitochondria is converted to acetoacetate by the action of HMG-CoA lyase

among the latter, in patients who were responsive (effective group) and non-responsive (ineffective group) after 2 weeks of treatment

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