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This is where the concept of bioavailability becomes critical

Oxidative stress due to these free radicals containing unpaired electrons can damage cells and the DNA leading to several diseases and even cancers, dementia, Alzheimers disease, Parkinsons disease and coronary heart disease

The consumption of PLP, which is involved in synthesizing serotonin and norepinephrine, reduces the risk of T2D, PD, and AD (when consumed with vitamins B9 & B12) [209,137]

[DOI] [PMC free article] [PubMed] [Google Scholar] 469.Wang X., Mou J.-H., Qin Z.-H., Hao T.-B., Zheng L., Buhagiar J., Liu Y.-H., Balamurugan S., He Y., Lin C.S.K., et al

doi: 10.1016/j.tips.2018.02.007 128 PhensyA.DriskillC.LindquistK.GuoL.JeevakumarV.FowlerB.et al

Phytofurans Under increased oxygen tension, such as in highly oxygenated tissues like lung, brain, and kidneys, cyclic nonenzymatic metabolites possessing a substituted tetrahydrofuran ring (PhytoFs) are preferentially formed compared to phytoprostanes