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3 Conventional and advanced models for studying MB biological properties It is becoming evident that some features of tumor cells are better resembled in vitro using three-dimensional (3D) cultures instead of conventional cell cultures in flat-bottomed plates with adherent cells to plastic or matrix substrate (106111)

Further transition into tumor involves the loss of 11q13, 13q21 and 14q32 [51]

Sleep disturbances, including insomnia or vivid dreams, have been reported by a small percentage of patients
